Bioestrovet Swine 0.0875 mg/ml Solution for Injection – SPC change

• Section 3.3: Do not use in cases of bronchospasm or gastrointestinal dysmotility.
• Section 3.4: The response of sows and gilts to induction of parturition may be influenced by the physiological state at the time of treatment. The vast majority of the animals, 95%, will commence farrowing within 36 hours of treatment. The majority of animals can be expected to respond within the period of 24+/- 5 hours following the injection, except in those cases where spontaneous parturition is imminent.
• Section 3.5: To reduce the risk of anaerobic infections arising from vasoconstriction at the injection site, injections into contaminated (wet or dirty) skin areas should be avoided. Thoroughly clean and disinfect injection sites prior to administration.

Injection into adipose tissue may lead to incomplete absorption of the veterinary medicinal product.

Premature induction of farrowing will reduce the piglet`s birth weight and increase the number of stillborn piglets and non-viable and immature born piglets. It is essential that the mean length of gestation is calculated on each farm from past records and not to anticipate the term of gestation by more than two days.

Do not administer intravenously.

• Section 3.7: Pregnancy: Do not administer to pregnant animals unless the objective is to terminate the pregnancy.

Fertility: There is no effect on the subsequent reproductive performance of sows treated with cloprostenol and of gilts or boars born from treated animals.

• Section 3.8: In animals to which a progestogen is being administered, a decrease in the response of cloprostenol can be expected.